Annotation Detail

Information
Associated Genes
P2RX7
Associated Variants
P2RX7 MUTATION
P2RX7 MUTATION
Associated Disease
Chronic esophagitis
Source Database
DisGeNET
Description
These results suggest that chronic esophagitis increases mRNA expressions of P2X3 and P2X7 receptors accompanied by up-regulation of TRPV1 and neurotrophic factors (NGF and GDNF).
Pubmed
25336328
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs