Annotation Detail
Information
- Associated Genes
- IGF1
- Associated Variants
-
IGF1 MUTATION
IGF1 MUTATION - Associated Disease
- Cardiac fibrosis
- Source Database
- DisGeNET
- Description
- Using a mouse model of ischemia-reperfusion, we demonstrate that intravenous delivery of Hoechst-IGF-1 results in activation of Akt, a downstream target of IGF-1 and protects from cardiac fibrosis and dysfunction following MI.
- Pubmed
- 24604065
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs