Annotation Detail

Information
Associated Genes
AGTR1
Associated Variants
AGT p.Met259Thr (p.M259T) ( ENST00000679957.1, ENST00000681514.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000679684.1, ENST00000366667.6 )
AGTR1 p.Leu191= (p.L191=) ( ENST00000349243.8, ENST00000402260.2, ENST00000404754.2, ENST00000418473.7, ENST00000461609.1, ENST00000474935.5, ENST00000475347.5, ENST00000497524.5 )
AGT p.Met259Thr (p.M259T) ( ENST00000366667.6, ENST00000679684.1, ENST00000679957.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000681514.1 )
AGTR1 p.Leu191= (p.L191=) ( ENST00000349243.8, ENST00000402260.2, ENST00000404754.2, ENST00000418473.7, ENST00000461609.1, ENST00000474935.5, ENST00000475347.5, ENST00000497524.5 )
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
Although the AGTR1 SNP did not show any association with WMLs, the interaction of the AGT rs699 and AGTR1 rs5182 SNPs with WMLs was significant before (P = 0.03) and after adjustment for hypertension (P = 0.045).
Pubmed
24622918
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.358635399942826
Year of publication
2015
Drugs