Annotation Detail
Information
- Associated Genes
- CHRNA5
- Associated Variants
-
CHRNA3 p.Tyr215= (p.Y215=)
(
ENST00000348639.7,
ENST00000326828.6 )
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000326828.6, ENST00000348639.7 ) - Associated Disease
- nicotine dependence
- Source Database
- DisGeNET
- Description
- A recent genome-wide association study demonstrated an association between a common polymorphism (rs1051730) in the nicotinic acetylcholine receptor gene cluster (CHRNA5-CHRNA3-CHRNB4) and both smoking quantity and nicotine dependence.
- Pubmed
- 19429911
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0196633669216207
- Year of publication
- 2009
Drugs