Annotation Detail

Information
Associated Genes
ALPP
Associated Variants
ALPP MUTATION
ALPP MUTATION
Associated Disease
renal carcinoma
Source Database
DisGeNET
Description
This is the first study that suggests deactivation of ERK1/2 by stimulation of ALP in renal cancer cell lines which can be used as a therapeutic target of RCC.
Pubmed
25241253
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs