Annotation Detail
Information
- Associated Genes
- ABO
- Associated Variants
-
ABO c.28+1349G>A
(
ENST00000538324.2,
ENST00000611156.4,
ENST00000679909.1 )
ABO c.28+1349G>A ( ENST00000538324.2, ENST00000611156.4, ENST00000679909.1 ) - Associated Disease
- Graves Disease
- Source Database
- DisGeNET
- Description
- In this study, we carried out a three-stage study in 9529 patients with GD and 9984 controls to identify new risk loci for GD and found genome-wide significant associations in the overall populations for five novel susceptibility loci: the GPR174-ITM2A at Xq21.1, C1QTNF6-RAC2 at 22q12.3-13.1, SLAMF6 at 1q23.2, ABO at 9q34.2 and an intergenic region harboring two non-coding RNAs at 14q32.2 and one previous indefinite locus, TG at 8q24.22 (Pcombined < 5 × 10(-8)).
- Pubmed
- 23612905
- Original source reporting the Gene Disease association
- GWASCAT
- DisGENET score for the Gene Disease association
- 0.122638473850682
- Year of publication
- 2014
Drugs