Annotation Detail

Information
Associated Genes
PAH
Associated Variants
PAH p.Arg408Trp (p.R408W) ( ENST00000307000.7, ENST00000553106.6 )
PAH p.Arg408Trp (p.R408W) ( ENST00000307000.7, ENST00000553106.6 )
Associated Disease
Classical phenylketonuria
Source Database
DisGeNET
Description
Different presentations of late-detected phenylketonuria in two brothers with the same R408W/R111X genotype in the PAH gene.
Pubmed
12542580
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.388522903896075
Year of publication
2003
Drugs