Annotation Detail

Information
Associated Genes
PAH
Associated Variants
PAH p.Arg408Trp (p.R408W) ( ENST00000307000.7, ENST00000553106.6 )
PAH p.Arg408Trp (p.R408W) ( ENST00000307000.7, ENST00000553106.6 )
Associated Disease
Phenylketonurias
Source Database
DisGeNET
Description
The R408W mutation in the phenylalanine hydroxylase gene (PAH) of phenylketonuria patients occurs on haplotypes 2.3 and 1.8 in Europeans.
Pubmed
7833927
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.374728566641762
Year of publication
1994
Drugs