Annotation Detail

Information
Associated Genes
VHL
Associated Variants
VHL p.His115Pro (p.H115P) ( ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1, ENST00000256474.3, ENST00000345392.3 )
VHL p.His115Arg (p.H115R) ( ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1, ENST00000256474.3, ENST00000345392.3, ENST00000696143.2 )
VHL p.His115Leu (p.H115L) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
VHL p.His115Pro (p.H115P) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
VHL p.His115Arg (p.H115R) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
VHL p.His115Leu (p.H115L) ( ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1, ENST00000256474.3 )
Associated Disease
Von Hippel-Lindau syndrome
Source Database
DisGeNET
Description
Based on this work, we propose that the nsSNP with a SNPid of rs5030812 is an important candidate for the cause of von Hippel-Lindau syndrome via the VHL gene.
Pubmed
18836774
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.658392405606355
Year of publication
2008
Drugs