Annotation Detail
Information
- Associated Genes
- MEN1
- Associated Variants
-
MEN1 MUTATION
MEN1 MUTATION - Associated Disease
- Well Differentiated Pancreatic Endocrine Tumor
- Source Database
- DisGeNET
- Description
- To elucidate the role of methylation of histone H3 at lysine 4 (H3K4) mediated by menin-HMT complexes during PanNET formation, genome-wide histone H3 lysine 4 trimethylation (H3K4me3) signals were mapped in pancreatic islets using unbiased chromatin immunoprecipitation coupled with next-generation sequencing (ChIP-seq).
- Pubmed
- 25537453
- Section of the abstract supporting the evidence
- UNLABELLED
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs