Annotation Detail
Information
- Associated Genes
- ADRB3
- Associated Variants
-
ADRB3 p.Trp64Arg (p.W64R)
(
ENST00000345060.5 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 ) - Associated Disease
- Metabolic syndrome X
- Source Database
- DisGeNET
- Description
- We recently identified a mutation in the human beta 3-adrenergic receptor (beta 3AR) gene (codon 64 TGGTrp -> CGGArg; TRP64ARG) that associates with features of the insulin resistance syndrome and an earlier onset of noninsulin-dependent diabetes mellitus (NIDDM).
- Pubmed
- 8923875
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0288277153555461
- Year of publication
- 1996
Drugs