Annotation Detail

Information
Associated Genes
ADRB3
Associated Variants
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
Associated Disease
Obesity, Morbid
Source Database
DisGeNET
Description
Additive effect of A-->G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta 3-adrenergic receptor gene on weight gain in morbid obesity.
Pubmed
8968850
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00845830529620761
Year of publication
1996
Drugs