Annotation Detail

Information
Associated Genes
ADRB3
Associated Variants
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
Associated Disease
obesity
Source Database
DisGeNET
Description
The aim of our study was to investigate the interaction of tryptophan-to-arginine (Trp64Arg) missense mutation in the beta3 adrenoreceptor (Beta3AR) with polymorphism in the UCP3 promotor (-55C->T) on insulin resistance in obese patients.
Pubmed
22774401
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.343344000998906
Year of publication
2012
Drugs