Annotation Detail
Information
- Associated Genes
- CHRNA3
- Associated Variants
-
PML c.1710+1786C>T
(
ENST00000436891.7,
ENST00000395135.7,
ENST00000435786.6,
ENST00000354026.10,
ENST00000395132.6,
ENST00000268059.10,
ENST00000565898.5,
ENST00000563500.5,
ENST00000268058.8,
ENST00000564428.5,
ENST00000569965.5,
ENST00000359928.8 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.377+1710A>G ( ENST00000348639.7, ENST00000326828.6 )
PML c.1710+1786C>T ( ENST00000268058.8, ENST00000268059.10, ENST00000354026.10, ENST00000359928.8, ENST00000395132.6, ENST00000395135.7, ENST00000435786.6, ENST00000436891.7, ENST00000563500.5, ENST00000564428.5, ENST00000565898.5, ENST00000569965.5 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.377+1710A>G ( ENST00000326828.6, ENST00000348639.7 ) - Associated Disease
- nicotine dependence
- Source Database
- DisGeNET
- Description
- One CHRNA5 (rs16969968) and two CHRNA3 (rs1051703, rs6495308) SNPs were examined for their ability to predict smokers who ever reported ND based on three phenotypic classifications: (1) 25+ CPD, (2) TTF < 10 min, and (3) HSI ≥ 4.
- Pubmed
- 22223462
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.133420203863774
- Year of publication
- 2012
Drugs