Annotation Detail

Information
Associated Genes
LCT
Associated Variants
MCM6 c.1917+326C>T ( ENST00000264156.3 )
MCM6 c.1917+326C>G ( ENST00000264156.3 )
MCM6 c.1917+326C>T ( ENST00000264156.3 )
MCM6 c.1917+326C>G ( ENST00000264156.3 )
Associated Disease
Lactase persistence
Source Database
DisGeNET
Description
In 97,811 individuals from the Danish general population, we examined the risk of incident type 2 diabetes and of overweight-obesity by milk intake observationally and by LCT-13910 C/T genotype [polymorphism (rs4988235) upstream from the lactase (LCT) gene], where TT and TC genotypes are associated with lactase persistence and CC with nonpersistence.
Pubmed
26156736
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0153202969683359
Year of publication
2015
Drugs