Annotation Detail
Information
- Associated Genes
- MSH6
- Associated Variants
-
MSH6 MUTATION
MSH6 MUTATION - Associated Disease
- Hereditary Nonpolyposis Colorectal Cancer
- Source Database
- DisGeNET
- Description
- C8 tracts were unstable in 2 of 4 MSH6-associated Lynch syndrome (LS) tumors, but all 4 showed complete MSH6 loss on immunohistochemistry.
- Pubmed
- 26099011
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,CLINVAR,GAD,ORPHANET
- DisGENET score for the Gene Disease association
- 0.277111591604881
Drugs