Annotation Detail

Information
Associated Genes
MUTYH
Associated Variants
MUTYH MUTATION
MUTYH MUTATION
Associated Disease
Hereditary Nonpolyposis Colorectal Cancer
Source Database
DisGeNET
Description
An additional 9 individuals carried mutations in other genes linked to high lifetime risks of cancer (5 had mutations in APC, 3 had bi-allelic mutations in MUTYH, and 1 had a mutation in STK11); all of these patients met NCCN criteria for Lynch syndrome testing.
Pubmed
25980754
Section of the abstract supporting the evidence
RESULTS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
11
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00325730246496364
Drugs