Annotation Detail

Information
Associated Genes
TLR9
Associated Variants
ENSG00000285082 c.140+4595C>T, TLR4 p.Thr399Ile (p.T399I) ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
ENSG00000285082 c.140+4595C>T, TLR4 p.Thr399Ile (p.T399I) ( ENST00000355622.8, ENST00000394487.5, ENST00000472304.2 )
Associated Disease
PHOTOPAROXYSMAL RESPONSE 1
Source Database
DisGeNET
Description
TLR 4 T399I and TLR9 -1486 T>C showed a positive association with seizures and photosensitivity, respectively.
Pubmed
25182168
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2015
Drugs