Annotation Detail

Information
Associated Genes
FLT3
Associated Variants
FLT3 MUTATION
FLT3 MUTATION
Associated Disease
Chronic myeloproliferative disorder
Source Database
DisGeNET
Description
Oncogenic mutations of FLT3 and KIT receptors are associated with poor survival in patients with acute myeloid leukemia (AML) and myeloproliferative neoplasms (MPNs), and currently available drugs are largely ineffective.
Pubmed
25456130
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs