Annotation Detail

Information
Associated Genes
ADD1
Associated Variants
ADD1 p.Gly460Trp (p.G460W) ( ENST00000264758.11, ENST00000398129.5, ENST00000683351.1 )
ADD1 p.Gly460Trp (p.G460W) ( ENST00000264758.11, ENST00000398129.5, ENST00000683351.1 )
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
The angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and the Adducin-1 (ADD1) G460W nonsense single nucleotide polymorphism (SNP) have previously been associated to hypertension, whereas their association with preeclampsia (PE) and gestational hypertension (GH) is still controversial.
Pubmed
19443911
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.320805664507023
Year of publication
2009
Drugs