Annotation Detail
Information
- Associated Genes
- SOD3
- Associated Variants
-
SOD3 MUTATION
SOD3 MUTATION - Associated Disease
- Degenerative disorder
- Source Database
- DisGeNET
- Description
- These findings showed for the first time that arginine 213 in the HBD of SOD3 is critical for maintaining proper organ function through moderating the normal innate immune response, which would otherwise lead to chronic inflammation and degenerative diseases in aged mice.
- Pubmed
- 25927599
- Section of the abstract supporting the evidence
- INNOVATION
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs