Annotation Detail

Information
Associated Genes
MAP2K1
Associated Variants
MAP2K1 MUTATION
MAP2K1 MUTATION
Associated Disease
Cardio-facio-cutaneous syndrome
Source Database
DisGeNET
Description
He was found to have a novel heterozygous missense variant (c.305A > G; p.E102G) in MAP2K1, a gene mostly causal for cardio-facio-cutaneous syndrome (CFCS).
Pubmed
25423878
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree,CTD_human,ORPHANET
DisGENET score for the Gene Disease association
0.244071628081205
Drugs