Annotation Detail
Information
- Associated Genes
- SMAD7
- Associated Variants
-
SMAD7 c.743-5183A>G
(
ENST00000262158.8,
ENST00000589634.1,
ENST00000591805.5 )
SLC22A3 c.975+8374G>T ( ENST00000275300.3 )
rs6983267 ( ENST00000645438.1 )
SMAD7 c.743-5183A>G ( ENST00000262158.8, ENST00000589634.1, ENST00000591805.5 )
SLC22A3 c.975+8374G>T ( ENST00000275300.3 )
rs6983267 ( ENST00000645438.1 ) - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- Moreover, we found cumulative effects of three genetic factors (rs7758229, rs6983267, and rs4939827 in SMAD7) and one environmental factor (alcohol drinking) which appear to increase CRC risk approximately twofold.
- Pubmed
- 21242260
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.162367471351159
- Year of publication
- 2011
Drugs