Annotation Detail
Information
- Associated Genes
- SOD2
- Associated Variants
-
SOD2 p.Val16Ala (p.V16A)
(
ENST00000337404.8,
ENST00000367054.6,
ENST00000367055.8,
ENST00000444946.6,
ENST00000452684.2,
ENST00000538183.7,
ENST00000546087.5 )
SOD2 p.Val16Ala (p.V16A) ( ENST00000337404.8, ENST00000367054.6, ENST00000367055.8, ENST00000444946.6, ENST00000452684.2, ENST00000538183.7, ENST00000546087.5 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- [Our results are consistent with the hypothesis that women with higher SOD2 antioxidant activity may experience less treatment-related toxicity but shorter time to disease recurrence or death after breast cancer adjuvant chemotherapy, supporting the modifying effects of oxidative stress-related enzymes on cancer treatment toxicity and efficacy.]
- Pubmed
- 20309628
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.0739532126892261
- Year of publication
- 2010
Drugs