Annotation Detail

Information
Associated Genes
MDM2
Associated Variants
MDM2 MUTATION
MDM2 MUTATION
Associated Disease
Atypical Lipoma
Source Database
DisGeNET
Description
Recently, a number of tumor-specific chromosome translocations and associated fusion genes have been identified in adipocytic tumors and atypical lipomatous tumors/well-differentiated liposarcomas (ALT/WDL), which have a supernumerary ring and/or giant chromosome marker with amplified sequences of the MDM2 and CDK4 genes.
Pubmed
24965044
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00380018620912425
Drugs