Annotation Detail
Information
- Associated Genes
- GPX1
- Associated Variants
-
SOD2 p.Val16Ala (p.V16A)
(
ENST00000337404.8,
ENST00000367054.6,
ENST00000367055.8,
ENST00000444946.6,
ENST00000452684.2,
ENST00000538183.7,
ENST00000546087.5 )
SOD2 p.Val16Ala (p.V16A) ( ENST00000337404.8, ENST00000367054.6, ENST00000367055.8, ENST00000444946.6, ENST00000452684.2, ENST00000538183.7, ENST00000546087.5 ) - Associated Disease
- Septicemia
- Source Database
- DisGeNET
- Description
- Evaluating the subgroup of 293 ICU patients with sepsis, a pooled analysis including two genetic variants GPx1 and SOD2 (47C>T SNP, rs4880; protein variant in MnSOD: Ala-9Val) showed a significant difference in relation to progression to septic shock.
- Pubmed
- 25497738
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs