Annotation Detail

Information
Associated Genes
MDM2
Associated Variants
MDM2 MUTATION
MDM2 MUTATION
Associated Disease
sarcoma
Source Database
DisGeNET
Description
MDM2/4 antagonists, on the other hand, are likely to be efficacious in malignancies in which MDM2 or MDM4 is overexpressed such as sarcomas, neuroblastomas and specific childhood leukemias.
Pubmed
25455730
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.0383229615716435
Drugs