Annotation Detail
Information
- Associated Genes
- SQSTM1
- Associated Variants
-
TGFB1 c.517-740G>T
(
ENST00000221930.6,
ENST00000600196.2,
ENST00000677934.1 )
RUNX3 c.59-8315G>C ( ENST00000338888.4, ENST00000399916.5 )
TGFB1 c.517-740G>T ( ENST00000221930.6, ENST00000600196.2, ENST00000677934.1 )
RUNX3 c.59-8315G>C ( ENST00000338888.4, ENST00000399916.5 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- After adjustment for multiple comparisons, two SNPs were significantly associated with breast cancer risk: RUNX3 (rs906296 ORCG/GG = 1.15 95 % CI 1.04-1.26) and TGF-β1 (rs4803455 ORCA/AA = 0.89 95 % CI 0.81-0.98).
- Pubmed
- 24036662
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
- Year of publication
- 2013
Drugs