Annotation Detail
Information
- Associated Genes
- IL6R
- Associated Variants
-
COL4A2 c.99+242A>G
(
ENST00000480609.2,
ENST00000360467.7,
ENST00000649951.2,
ENST00000617564.3,
ENST00000714396.1,
ENST00000714399.1,
ENST00000619688.3,
ENST00000649101.1,
ENST00000494852.3,
ENST00000650540.1,
ENST00000400163.8 )
FLT1 c.1552-2416C>T ( ENST00000541932.5, ENST00000615840.5, ENST00000639477.1, ENST00000282397.9 )
IL6R c.997-320T>C ( ENST00000344086.8, ENST00000368485.8 )
COL4A2 c.99+242A>G ( ENST00000360467.7, ENST00000400163.8, ENST00000480609.2, ENST00000494852.3, ENST00000617564.3, ENST00000619688.3, ENST00000649101.1, ENST00000649951.2, ENST00000650540.1, ENST00000714396.1, ENST00000714399.1 )
FLT1 c.1552-2416C>T ( ENST00000282397.9, ENST00000541932.5, ENST00000615840.5, ENST00000639477.1 )
IL6R c.997-320T>C ( ENST00000344086.8, ENST00000368485.8 ) - Associated Disease
- Dyslipidemias
- Source Database
- DisGeNET
- Description
- Multivariable logistic regression analysis with adjustment for age, sex, body mass index, and the prevalence of smoking, hypertension, diabetes mellitus, and dyslipidaemia revealed that rs4845625 of IL6R (P = 0.0008; dominant model; odds ratio, 1.49), rs4773144 of COL4A1 (P = 0.0252; dominant model; odds ratio, 1.28), and rs9319428 of FLT1 (P = 0.0260: additive model; odds ratio, 0.77) were significantly associated with CKD.
- Pubmed
- 25524550
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2014
Drugs