Annotation Detail
Information
- Associated Genes
- TLR2
- Associated Variants
-
TLR2 c.-1555+1614T>A
(
ENST00000260010.7,
ENST00000642580.1,
ENST00000642700.2,
ENST00000643501.2,
ENST00000646219.2,
ENST00000646900.2,
ENST00000714431.1,
ENST00000714432.1,
ENST00000714433.1,
ENST00000714434.1,
ENST00000714435.1,
ENST00000714436.1 )
TLR2 c.-1555+1614T>A ( ENST00000260010.7, ENST00000642580.1, ENST00000642700.2, ENST00000643501.2, ENST00000646219.2, ENST00000646900.2, ENST00000714431.1, ENST00000714432.1, ENST00000714433.1, ENST00000714434.1, ENST00000714435.1, ENST00000714436.1 ) - Associated Disease
- asthma
- Source Database
- DisGeNET
- Description
- The risk of having doctor-diagnosed asthma increased with increasing PM(2.5) levels in children with at least one copy of the TLR2 rs4696480 A allele (OR 2.0 (95% CI 1.2 to 3.1) for an interquartile range increase in exposure).
- Pubmed
- 20685742
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.033647655704535
- Year of publication
- 2010
Drugs