Annotation Detail
Information
- Associated Genes
- BRCA1
- Associated Variants
-
BRCA1 MUTATION
BRCA1 MUTATION - Associated Disease
- Malignant neoplasm of ovary
- Source Database
- DisGeNET
- Description
- Approximately 12.9% of all ovarian cancers in Ontario occur in the 0.7% of women in the general population who have a lifetime ovarian cancer risk in excess of 5%, the majority of whom carry a mutation in BRCA1 or BRCA2.
- Pubmed
- 26341709
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 12
- Original source reporting the Gene Disease association
- BeFree,GAD,UNIPROT
- DisGENET score for the Gene Disease association
- 0.28
Drugs