Annotation Detail

Information
Associated Genes
GSTP1
Associated Variants
GSTP1 MUTATION
GSTP1 MUTATION
Associated Disease
Gastrooesophageal cancer
Source Database
DisGeNET
Description
Germline polymorphisms of DPYD, TYMS and GSTP1 have a significant effect on toxicity and clinical outcome in patients receiving capecitabine-based chemotherapy for advanced colorectal or gastroesophageal cancer.
Pubmed
25677447
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs