Annotation Detail

Information
Associated Genes
CYBA
Associated Variants
CYBA p.Tyr72His (p.Y72H) ( ENST00000696162.1, ENST00000696157.1, ENST00000696161.1, ENST00000696156.1, ENST00000261623.8, ENST00000696158.1, ENST00000569359.5, ENST00000696163.1, ENST00000696159.1, ENST00000567174.5, ENST00000696160.1 )
ENSG00000250349 c.171+359172C>G, CYBB c.252+1572C>G ( ENST00000378588.5, ENST00000696171.1 )
CYBA p.Tyr72His (p.Y72H) ( ENST00000261623.8, ENST00000567174.5, ENST00000569359.5, ENST00000696156.1, ENST00000696157.1, ENST00000696158.1, ENST00000696159.1, ENST00000696160.1, ENST00000696161.1, ENST00000696162.1, ENST00000696163.1 )
ENSG00000250349 c.171+359172C>G, CYBB c.252+1572C>G ( ENST00000378588.5, ENST00000696171.1 )
Associated Disease
Sleep Apnea, Obstructive
Source Database
DisGeNET
Description
The frequencies of NADPH oxidase (NOX) polymorphisms in the p22phox subunit were similar between children with OSA and controls, except for rs6520785 and rs4673, the latter being significantly more frequent among the OSA children without deficits than with deficits (p<0.02).
Pubmed
21902598
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00318135759484294
Year of publication
2012
Drugs