Annotation Detail

Information
Associated Genes
FGFR3
Associated Variants
FGFR3 p.Pro250Arg (p.P250R) ( ENST00000340107.9, ENST00000412135.7, ENST00000352904.6, ENST00000440486.8, ENST00000481110.7 )
FGFR3 p.Pro250Arg (p.P250R) ( ENST00000340107.9, ENST00000352904.6, ENST00000412135.7, ENST00000440486.8, ENST00000481110.7 )
Associated Disease
craniosynostosis
Source Database
DisGeNET
Description
The Pro250Arg mutation in the FGFR3 gene is found in patients with Muenke syndrome and is one of the most frequently encountered mutations in craniosynostosis syndromes.
Pubmed
21403557
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0301275047575036
Year of publication
2011
Drugs