Annotation Detail
Information
- Associated Genes
- IFNGR1
- Associated Variants
-
IFNGR1 MUTATION
IFNGR1 MUTATION - Associated Disease
- Metastatic Prostate Carcinoma
- Source Database
- DisGeNET
- Description
- In MYC-driven, but not PI3K-driven prostate cancer, we show that interferon-γ receptor 1 (IFNGR1) is directly repressed by EZH2 in a MYC-dependent manner and is downregulated in a subset of metastatic prostate cancers.
- Pubmed
- 24953652
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs