Annotation Detail
Information
- Associated Genes
- GGH
- Associated Variants
-
GGH MUTATION
GGH MUTATION
SLC19A1 p.His27Arg (p.H27R) ( ENST00000311124.9, ENST00000380010.8, ENST00000567670.5, ENST00000650808.1 )
SLC19A1 p.His27Arg (p.H27R) ( ENST00000311124.9, ENST00000380010.8, ENST00000567670.5, ENST00000650808.1 ) - Associated Disease
- rheumatoid arthritis
- Source Database
- DisGeNET
- Description
- We investigated whether polymorphisms in reduced folate carrier (SLC19A1 G80A) and gamma-glutamyl-hydrolase (GGH-401C/T) are predictive of methotrexate polyglutamate (MTXPG) levels in patients with rheumatoid arthritis treated with weekly low-dose methotrexate (MTX).
- Pubmed
- 15564880
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.130011011658569
- Year of publication
- 2004
Drugs