Annotation Detail
Information
- Associated Genes
- TPH2
- Associated Variants
-
rs4570625
rs4570625 - Associated Disease
- PANIC DISORDER 1
- Source Database
- DisGeNET
- Description
- In this study involving 64 individuals, we examined the associations between prefrontal cortical GABA concentration and 12 single nucleotide polymorphisms (SNPs) spanning the TPH2 gene, including rs4570625 (-703 G/T SNP), a potentially functional TPH2 polymorphism that has been associated with decreased TPH2 mRNA expression and panic disorder.
- Pubmed
- 23552096
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
- Year of publication
- 2014
Drugs