Annotation Detail

Information
Associated Genes
TSC2
Associated Variants
TSC2 p.Arg1200Trp (p.R1200W) ( ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000382538.10, ENST00000350773.9, ENST00000219476.9, ENST00000642797.1, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
TSC2 p.Arg1200Trp (p.R1200W) ( ENST00000219476.9, ENST00000350773.9, ENST00000382538.10, ENST00000401874.7, ENST00000439673.6, ENST00000568454.6, ENST00000642206.2, ENST00000642365.2, ENST00000642561.1, ENST00000642797.1, ENST00000642936.1, ENST00000643088.1, ENST00000643946.1, ENST00000644043.1, ENST00000644329.1, ENST00000644335.1, ENST00000645186.2, ENST00000646388.1 )
Associated Disease
tuberous sclerosis
Source Database
DisGeNET
Description
Functional characterization of the TSC2 c.3598C>T (p.R1200W) missense mutation that co-segregates with tuberous sclerosis complex in mildly affected kindreds.
Pubmed
21332470
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.4938153829769
Year of publication
2012
Drugs