Annotation Detail

Information
Associated Genes
HNF1B
Associated Variants
HNF1B c.544+1391T>C ( ENST00000613727.4, ENST00000621123.4, ENST00000614313.4, ENST00000617811.5 )
HNF1B c.544+1391T>C ( ENST00000613727.4, ENST00000614313.4, ENST00000617811.5, ENST00000621123.4 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
We identified an endometrial cancer susceptibility locus close to HNF1B at 17q12 (rs4430796, P = 7.1 × 10(-10)) that is also associated with risk of prostate cancer and is inversely associated with risk of type 2 diabetes.
Pubmed
21499250
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.564132095956303
Year of publication
2011
Drugs