Annotation Detail
Information
- Associated Genes
- SLCO6A1
- Associated Variants
-
SLCO6A1 MUTATION
SLCO6A1 MUTATION - Associated Disease
- Carcinogenicity
- Source Database
- DisGeNET
- Description
- The metabolism of dichloromethane proceeds through a Theta-class glutathione S-transferase (GST) T1-1-catalyzed pathway, where its reactive intermediates have been implicated in genotoxicity and carcinogenicity.
- Pubmed
- 25197345
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs