Annotation Detail
Information
- Associated Genes
- ACE
- Associated Variants
-
ACE MUTATION
ACE MUTATION - Associated Disease
- Coughing
- Source Database
- DisGeNET
- Description
- rs4340 polymorphism at intron 16 of the angiotensin-converting enzyme (CD143) gene was reported to repress cough reflex by reducing bradykinin and substance P levels, thus increasing the likelihood to develop pneumonia.
- Pubmed
- 26222869
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.135168407228094
- Year of publication
- 2015
Drugs