Annotation Detail
Information
- Associated Genes
- AGT
- Associated Variants
-
ACE c.1488-58T>C
(
ENST00000428043.5,
ENST00000290866.10 )
ENSG00000264813 p.Thr202= (p.T202=), ACE p.Thr776= (p.T776=) ( ENST00000290863.10, ENST00000413513.7, ENST00000290866.10, ENST00000428043.5 )
AGT p.Met259Thr (p.M259T) ( ENST00000679957.1, ENST00000681514.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000679684.1, ENST00000366667.6 )
ACE c.1488-58T>C ( ENST00000290866.10, ENST00000428043.5 )
ENSG00000264813 p.Thr202= (p.T202=), ACE p.Thr776= (p.T776=) ( ENST00000290863.10, ENST00000290866.10, ENST00000413513.7, ENST00000428043.5 )
AGT p.Met259Thr (p.M259T) ( ENST00000366667.6, ENST00000679684.1, ENST00000679957.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000681514.1 ) - Associated Disease
- Kidney Diseases
- Source Database
- DisGeNET
- Description
- ACE ID/DD genotypes in combination with ACE rs4311, rs4343, and AGT rs699 mutant genotypes increased the risk of DNP development fourfold (p < 0.01).
- Pubmed
- 19108684
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.152975288306871
- Year of publication
- 2009
Drugs