Annotation Detail
Information
- Associated Genes
- PTGS1
- Associated Variants
-
PTGS1 MUTATION
PTGS1 MUTATION - Associated Disease
- Endothelial dysfunction
- Source Database
- DisGeNET
- Description
- Pharmacological inhibition of cyclooxygenase-2 (COX-2) but not COX-1 prevented endothelial dysfunction, and ROS scavengers reduced COX-2 mRNA and protein expression in spontaneously hypertensive rats (SHR) renal arteries.
- Pubmed
- 24328731
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs