Annotation Detail

Information
Associated Genes
ACE
Associated Variants
NC_000017.11:g.63476833T>A
NC_000017.11:g.63476833T>A
Associated Disease
Cardiovascular Diseases
Source Database
DisGeNET
Description
We could show that SNP rs4291 influences ACE activity and HPA-axis hyperactivity and might therefore represent a common pathophysiologic link for unipolar depression and cardiovascular disease.
Pubmed
16924268
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.260603275002322
Year of publication
2006
Drugs