Annotation Detail

Information
Associated Genes
ACE
Associated Variants
NC_000017.11:g.63476833T>A
NC_000017.11:g.63476833T>A
Associated Disease
Cardiovascular Diseases
Source Database
DisGeNET
Description
The ACE rs4291 TT genotype, which has been associated with HPA axis hyperactivity and higher levels of serum angiotensin converting enzyme (ACE), predicted acute stress response and reports of physician-diagnosed CVD in a national sample following collective stress.
Pubmed
23055331
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.260603275002322
Year of publication
2012
Drugs