Annotation Detail

Information
Associated Genes
CFTR
Associated Variants
CFTR MUTATION
CFTR MUTATION
Associated Disease
Pseudomonas aeruginosa infection
Source Database
DisGeNET
Description
Pseudomonas aeruginosa infections of the airway cells decrease apical expression of both wild-type (wt) and F508del CFTR through the inhibition of apical endocytic recycling.
Pubmed
24595473
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Drugs