Annotation Detail
Information
- Associated Genes
- MDM4
- Associated Variants
-
MDM4 c.*32C>A
(
ENST00000612738.4,
ENST00000367183.7,
ENST00000391947.6,
ENST00000616250.4,
ENST00000367182.8,
ENST00000614459.4,
ENST00000454264.6 )
MDM4 c.*32C>A ( ENST00000367182.8, ENST00000367183.7, ENST00000391947.6, ENST00000454264.6, ENST00000612738.4, ENST00000614459.4, ENST00000616250.4 ) - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- SNPs at four loci, 1q32.1 (MDM4, P = 2.1 × 10(-12) and LGR6, P = 1.4 × 10(-8)), 2p24.1 (P = 4.6 × 10(-8)) and 16q12.2 (FTO, P = 4.0 × 10(-8)), were associated with ER-negative but not ER-positive breast cancer (P > 0.05).
- Pubmed
- 23535733
- Original source reporting the Gene Disease association
- GWASCAT
- DisGENET score for the Gene Disease association
- 0.133148761991693
- Year of publication
- 2013
Drugs