Annotation Detail

Information
Associated Genes
PNPLA3
Associated Variants
PNPLA3 p.Ile148Met (p.I148M) ( ENST00000216180.8, ENST00000423180.2 )
GCKR c.1423-418T>C ( ENST00000264717.7 )
rs4240624
PNPLA3 p.Ile148Met (p.I148M) ( ENST00000216180.8, ENST00000423180.2 )
GCKR c.1423-418T>C ( ENST00000264717.7 )
rs4240624
Associated Disease
Fatty Liver
Source Database
DisGeNET
Description
We used data from the National Health and Nutrition Examination Survey III to validate the association between rs738409 (PNPLA3), rs780094 (GCKR), and rs4240624 (PPP1R3B) with HS, with or without increased levels of ALT, among 3 different ancestries.
Pubmed
23416328
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.162529292613064
Year of publication
2013
Drugs