Annotation Detail

Information
Associated Genes
NR1I2
Associated Variants
NR1I2 MUTATION
NR1I2 MUTATION
Associated Disease
Helicobacter pylori infection
Source Database
DisGeNET
Description
PAR1 suppression of IRF5 and IL-12/23 secretion by macrophages provides a novel mechanism by which the host suppresses the mucosal Th1 and Th17 response to H. pylori infection.
Pubmed
24866378
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs