Annotation Detail

Information
Associated Genes
NR3C2
Associated Variants
NR3C2 p.Ser810Leu (p.S810L) ( ENST00000344721.8, ENST00000358102.8, ENST00000511528.1, ENST00000512865.5, ENST00000625323.2 )
NR3C2 p.Ser810Leu (p.S810L) ( ENST00000344721.8, ENST00000358102.8, ENST00000511528.1, ENST00000512865.5, ENST00000625323.2 )
Associated Disease
Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy
Source Database
DisGeNET
Description
Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy.
Pubmed
10884226
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.36
Year of publication
2000
Drugs